Plants of the Gods- Psychedelics







LET US EXPLORE A BRIEF HISTORY OF PSYCHEDELICS 

Psychedelics are a class of drugs that alter perception, thought, and mood, and can produce intense sensory experiences. They work by changing the way neurotransmitters, which are chemical messengers in the brain, interact with neural circuits. This leads to changes in the way the brain processes information and can result in altered states of consciousness.

Some of the most well-known psychedelics include LSD, psilocybin (found in magic mushrooms), and DMT (found in ayahuasca). These substances have been used for thousands of years in various cultural and religious contexts for their perceived healing and transformative properties.

In recent years, there has been growing interest in the potential therapeutic benefits of psychedelics for a range of mental health conditions, including depression, anxiety, and PTSD. Preliminary studies have shown promising results, and clinical trials are currently underway to explore their potential as treatments.

THE DISCOVERY 

The discovery of LSD in 1938 by Swiss chemist Albert Hofmann, psychedelics have been the subject of much scientific research and cultural interest. In the 1950s and 1960s, researchers conducted numerous studies on the therapeutic potential of psychedelics, particularly in the treatment of mental health disorders such as depression, anxiety, and addiction.

Concerns about their potential for abuse and their association with the counterculture movement, the use of psychedelics was criminalized in many countries, including the United States, in the 1970s. This led to a decades-long hiatus in research on the therapeutic potential of psychedelics.

In recent years, there has been a renewed interest in psychedelics as a potential treatment for a range of mental health conditions. This has led to a growing body of research on the therapeutic use of psychedelics, particularly in the treatment of depression, anxiety, post-traumatic stress disorder (PTSD), and addiction.

Studies have shown promising results, with some researchers suggesting that psychedelics could be a breakthrough treatment for mental health disorders that have proven difficult to treat with conventional medications. In 2020, the  (FDA) granted breakthrough therapy status to psilocybin, a psychedelic compound found in certain species of mushrooms, for the treatment of depression.

While the use of psychedelics for therapeutic purposes remains controversial, the growing body of research suggests that they may have a valuable role to play in the treatment of mental health conditions. I seek outls need accuratek out accurate information and resources if they have questions or concerns about the use of these substances.



EAST AFRICA 

In East Africa, including Tanzania, the use of traditional psychoactive plants and substances has been documented in various cultures for centuries. For example, the Maasai people of Tanzania and Kenya have used the root of the "oloololo" plant, which contains psychoactive compounds, in their rituals and ceremonies for generations.

In Southern Africa, traditional healers and shamans have used psychoactive substances in their spiritual practices for centuries. The use of the "iboga" plant in Gabon and the "umhlonyane" plant in South Africa are just a few examples.

The use of these substances in traditional cultural and religious contexts is generally accepted, but the use of modern synthetic psychedelics is illegal in Tanzania and carries serious legal consequences.

Despite this, there has been a growing interest in psychedelic research and therapy in Tanzania and other parts of Africa. In recent years, organizations such as the African Coalition for Safe Access to Psychedelics (ACSAP) have emerged to promote education, research, and advocacy for the responsible use of psychedelics in Africa.


ALBERT HOFMAN  INPUTS TO MODERN SCIENCE 

Albert Hofmann's discovery of LSD in 1900' and his subsequent exploration of its effects on the mind and body, helped to change the drug world in a number of ways.

  • First, Hofms everseveralpened up new avenues of scientific research into the mind and consciousness, as well as into the therapeutic potential of psychedelics. This research has led to the development of new forms of therapy, such as psychedelic-assisted therapy, which are now being used to treat a variety of mental health condition

  • Second, Hofmann's discovery helped to usher in the counterculture of the 1960s, which was characterized in part by experimentation with psychedelic drugs like LSD. This experimentation helped to change the way that people thought about drugs, leading to a greater acceptance of alternative forms of consciousness exploration and a shift away from the traditional view of drugs as inherently dangerous and addi inherently

  • To inspire a new generation of researchers and thinkers who are continuing to explore the potential of psychedelics for understanding the mind, consciousness, and the nature of reality itself. Today, a growing number of scientists, medical professionals, and others are working to advance the field of psychedelic research and explore the potential of te substances for improving mental health and well-being.


Food for thought:

  • Research has shown that the use of psychedelics can have significant benefits in treating certain mental health conditions. For example, a study conducted at Johns Hopkins University found that a single dose of psilocybin, the active ingredient in "magic mushrooms," was effective in reducing depression and anxiety in cancer patients for up to six months after treatment. Another study found that MDMA-assisted psychotherapy was effective in reducing symptoms of post-traumatic stress disorder (PTSD) in veterans and first responders.

  • According to the World Health Organization, depression is a leading cause of disability worldwide, affecting more than 264 million people. PTSD is another significant public health issue, with an estimated 10% of people experiencing the disorder at some point in their lives



Sources:

 

Johnson, M. W., Garcia-Romeu, A., Cosimano, M. P., & Griffiths, R. R. (2014). A pilot study of the 5-HT2AR agonist psilocybin in the treatment of tobacco addiction. Journal of Psychopharmacology, 28(11), 983-992. doi:10.1177/0269881114548296  

Carhart-Harris, R. L., Bolstridge, M., Rucker, J., Day, C. M., Erritzoe, D., Kaelen, M., . . . Nutt, D. J. (2016). Psilocybin with psychological support for treatment-resistant depression: An open-label feasibility study. The Lancet Psychiatry, 3(7), 619-627. doi:10.1016/S2215-0366(16)30065-7  

United States Food and Drug Administration. (2020, November 17). FDA grants breakthrough therapy designation to Usona Institute's psilocybin program for major depressive disorder. Retrieved from https://www.fda.gov/news-events/press-announcements/fda-grants-breakthrough-therapy-designation-usona-institutes-psilocybin-program-major-depressive

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